RNA families database of alignments and CMs   Rfam Home Page

Switch to the new Rfam website We are currently developing a new website for Rfam. All new data releases will be available through the new site, but this website will remain on Rfam release 8.1 and will no longer be updated. If you would like to see data from Rfam release 9.0, please use the new site, at http://rfam.sanger.ac.uk/ Rfam is a joint project involving researchers based at the Wellcome Trust Sanger Institute, Cambridge, UK and Janelia Farm, Ashburn, VA, USA. Rfam is a large collection of multiple sequence alignments and covariance models covering many common non-coding RNA families. For each family in Rfam you can: View and download multiple sequence alignments Read family annotation Examine species distribution of family members Follow links to otherdatabases In conjunction with the INFERNAL software suite, Rfam can be used to annotate sequences (including complete genomes) for homologues to known non-coding RNAs. Please read important information about using Rfam for genome annotation. We provide pre-calculated lists of putative RNAs in over 400 complete genomes, and a web search facility for short sequences. Rfam makes use of a large amount of available data, especially published multiple sequence alignments, and repackages these data in a single searchable and sustainable resource. We have made every effort to credit individual sources on family pages, and have compiled a list of links to these sources here. If you find any of the data presented here useful, please also be sure to credit the primary source. For more information on Rfam, and using this site, click here.

Version 8.1 October 2007, 607 families Enter your keyword(s) here   Enter an EMBL name or accession number

Rfam Mirror Servers Worldwide Sanger Institute (UK) Janelia Farm (USA)   FTP access to Rfam You can also download the Rfam database and for instance search it locally using the INFERNAL covariance model software. Hyperlink directly to the ftp site or View ftp site files References If you find Rfam useful, please cite the following publication: Rfam: annotating non-coding RNAs in complete genomes. Sam Griffiths-Jones, Simon Moxon, Mhairi Marshall, Ajay Khanna, Sean R. Eddy and Alex Bateman. Nucleic Acids Res. 2005 33:D121-D124.

Comments or questions on the site? Send a mail to rfam@sanger.ac.uk