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MATCH-BOX - The Match-Box software proposes protein sequence multiple alignment tools based on strict statistical criteria. The method circumvents the gap penalty requirement: in the Match-Box method, gaps are the result of the alignment and not a governing parameter of the matching procedure. A reliability score is provided below each aligned position. The Match-Box program is particularly suitable for finding and aligning conserved structural motives, in particular in protein core.
Ask for a free Match-Box trial software
: Company providing bioinformatics services.
Data and parameters input for the Match-Box server:
Information about the Match-Box server:
MATCH-BOX - Simultaneous alignment of several protein sequences where each aligned position is weighted by a reliability score.
Please send comments and enquiries to:
Prof. Eric Depiereux
University of Namur : Tel: +32-81-72-44-15
Laboratoire BMS : Fax: +32-81-72-44-01
Rue de Bruxelles, 61 : E-mail: matchbox-help@fundp.ac.be
5000 Namur, Belgium :
Co-workers
- Ernest Feytmans, The University of the West Indies
- Carla Vinals, Guy Baudoux & Pascal Briffeuil
- Xavier de Bolle, Isabelle Reginster, Facultés Universitaires, Namur
- Eric Chavet & Christophe Golenvaux, Lambda-Plus, Les Isnes
Project supported by the Walloon Government , Federal State of Belgium.
Bibliography:
- Depiereux, E. & Feytmans, E.
Simultaneous and multivariate alignment of protein sequences: correspondance between physicochemical profiles and structurally conserved regions (SCR).
Prot. Engng. 4(6):603-613 (1991)
- Depiereux, E. & Feytmans, E.
MATCH-BOX - A fundamentally new algorithm for the simultaneous alignment of several protein sequences.
Comput. Appl. Biosci. 8(5):501-509 (1992)
- Depiereux, E., Baudoux, G., Briffeuil, P., Reginster, I.,De Bolle, X., Vinals, C., Feytmans, E.
Match-Box_server: a multiple sequence alignment tool placing emphasis on reliability.
Comput. Appl. Biosci. 13(3):249-256 (1997)
- Briffeuil, P., Baudoux, G., Lambert, C., De Bolle, X., Vinals, C., Feytmans, E. and Depiereux, E.
Comparative analysis of seven multiple protein sequence alignment servers: clues to enhance predictions reliability.
Bioinformatics. 14(4):357-366 (1998)
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